Integrated single-cell and bulk RNA sequencing analysis identifies a cancer-associated fibroblast-related gene signature for predicting survival and therapy in gastric cancer
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As the dominant component of the tumor microenvironment, cancer-associated fibroblasts (CAFs), play a vital role in tumor progression. An increasing number of studies have confirmed that CAFs are involved in almost every aspect of tumors including tumorigenesis, metabolism, invasion, metastasis and drug resistance, and CAFs provide an attractive therapeutic target.
Nội dung trích xuất từ tài liệu:
Integrated single-cell and bulk RNA sequencing analysis identifies a cancer-associated fibroblast-related gene signature for predicting survival and therapy in gastric cancer
Nội dung trích xuất từ tài liệu:
Integrated single-cell and bulk RNA sequencing analysis identifies a cancer-associated fibroblast-related gene signature for predicting survival and therapy in gastric cancer
Tìm kiếm theo từ khóa liên quan:
BMC Cancer Cancer-associated fibroblasts Gastric cancer Single-cell RNA sequencing Gene signature Small molecular drug Tumor microenvironmentGợi ý tài liệu liên quan:
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