Integrative epigenomic and highthroughput functional enhancer profiling reveals determinants of enhancer heterogeneity in gastric cancer
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Enhancers are distal cis-regulatory elements required for cell-specific gene expression and cell fate determination. In cancer, enhancer variation has been proposed as a major cause of inter-patient heterogeneity— however, most predicted enhancer regions remain to be functionally tested.
Nội dung trích xuất từ tài liệu:
Integrative epigenomic and highthroughput functional enhancer profiling reveals determinants of enhancer heterogeneity in gastric cancer
Nội dung trích xuất từ tài liệu:
Integrative epigenomic and highthroughput functional enhancer profiling reveals determinants of enhancer heterogeneity in gastric cancer
Tìm kiếm theo từ khóa liên quan:
Genome medicine Enhancer landscape Gastric cancer Enhancer-promoter interactions Enhancer heterogeneityGợi ý tài liệu liên quan:
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