NucHMM: A method for quantitative modeling of nucleosome organization identifying functional nucleosome states distinctly associated with splicing potentiality
Số trang: 17
Loại file: pdf
Dung lượng: 2.76 MB
Lượt xem: 3
Lượt tải: 0
Xem trước 2 trang đầu tiên của tài liệu này:
Thông tin tài liệu:
We develop a novel computational method, NucHMM, to identify functional nucleosome states associated with cell type-specific combinatorial histone marks and nucleosome organization features such as phasing, spacing and positioning. We test it on publicly available MNase-seq and ChIP-seq data in MCF7, H1, and IMR90 cells and identify 11 distinct functional nucleosome states.
Nội dung trích xuất từ tài liệu:
NucHMM: A method for quantitative modeling of nucleosome organization identifying functional nucleosome states distinctly associated with splicing potentiality
Nội dung trích xuất từ tài liệu:
NucHMM: A method for quantitative modeling of nucleosome organization identifying functional nucleosome states distinctly associated with splicing potentiality
Tìm kiếm theo từ khóa liên quan:
Genome Biology Nucleosome organization Hidden Markov model Splicing potentiality Novel computational method Functional nucleosome statesGợi ý tài liệu liên quan:
-
Development of Vietnamese speech synthesis system using deep neural networks
15 trang 20 0 0 -
MLFNN algorithm for speech classification using MMFC feature extraction in a smart wheelchair
7 trang 19 0 0 -
Gene-level differential analysis at transcript-level resolution
11 trang 16 0 0 -
HistoneHMM: Differential analysis of histone modifications with broad genomic footprints
15 trang 12 0 0 -
5 trang 10 0 0
-
24 trang 9 0 0
-
18 trang 8 0 0
-
Guidelines for benchmarking of optimization-based approaches for fitting mathematical models
10 trang 7 0 0 -
Recurrent evolution of heat-responsiveness in Brassicaceae COPIA elements
15 trang 7 0 0 -
Evolution of plant genome architecture
14 trang 7 0 0