P53R2 as a novel prognostic biomarker in nasopharyngeal carcinoma
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p53R2 is a target of p53 gene, which is essential for DNA repair, mitochondrial DNA synthesis, protection against oxidative stress, chromosomal instability, chronic inflammation and tumorigenesis. This study is aimed to investigate the expression of ribonucleotide reductase (RR) subunit p53R2 in nasopharyngeal carcinoma and its significance in the prognosis.
Nội dung trích xuất từ tài liệu:
P53R2 as a novel prognostic biomarker in nasopharyngeal carcinoma
Nội dung trích xuất từ tài liệu:
P53R2 as a novel prognostic biomarker in nasopharyngeal carcinoma
Tìm kiếm theo từ khóa liên quan:
BMC Cancer Nasopharyngeal carcinoma DNA repair Mitochondrial DNA synthesis Oxidative stress Chromosomal instabilityGợi ý tài liệu liên quan:
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