PCDH17 gene promoter methylation status in a cohort of Egyptian women with epithelial ovarian cancer
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Ovarian cancer is a leading cause of female mortality. Epigenetic changes occur in early stages of carcinogenesis and represent a marker for cancer diagnosis. Protocadherin 17 (PCDH17) is a tumor suppressor gene involved in cell adhesion and apoptosis. The aim of the study was to compare the methylation status of PCDH17 gene promoter between females diagnosed with epithelial ovarian cancer and a control group composed of normal and benign ovarian lesions.
Nội dung trích xuất từ tài liệu:
PCDH17 gene promoter methylation status in a cohort of Egyptian women with epithelial ovarian cancer
Nội dung trích xuất từ tài liệu:
PCDH17 gene promoter methylation status in a cohort of Egyptian women with epithelial ovarian cancer
Tìm kiếm theo từ khóa liên quan:
BMC Cancer Ovarian cancer DNA methylation Cancer diagnosis Cell adhesion PCDH17 gene promoterTài liệu liên quan:
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