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Peptic Ulcer Disease in Children

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Lesions associated with left to right shunt, such as AVSD, cause high pulmonary blood flow and congestive cardiac failure. The normal physiological response to high pulmonary blood flow is for the pulmonary vascular resistance to increase. With time, the pulmonary vascular resistance will exceed the systemic vascular resistance, and the flow across the shunt will reverse (Eisenmenger’s syndrome). Clinically, this is associated with an initial improvement in symptoms of cardiac failure as pulmonary blood flow reduces, followed by increasing cyanosis as the shunt reverses to become right to left. Surgical closure of the shunt is not possible at this stage...
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Peptic Ulcer Disease in Children

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