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Quantifying substantial carcinogenesis of genetic and environmental factors from measurement error in the number of stem cell divisions

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The relative contributions of genetic and environmental factors versus unavoidable stochastic risk factors to the variation in cancer risk among tissues have become a widely-discussed topic. Some claim that the stochastic effects of DNA replication are mainly responsible, others believe that cancer risk is heavily affected by environmental and hereditary factors.
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Quantifying substantial carcinogenesis of genetic and environmental factors from measurement error in the number of stem cell divisions

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