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Role of pelitinib in the regulation of migration and invasion of hepatocellular carcinoma cells via inhibition of Twist1
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Overexpression of Twist1, one of the epithelial-mesenchymal transition-transcription factors (EMTTFs), is associated with hepatocellular carcinoma (HCC) metastasis. Pelitinib is known to be an irreversible epidermal growth factor receptor tyrosine kinase inhibitor that is used in clinical trials for colorectal and lung cancers, but the role of pelitinib in cancer metastasis has not been studied.
Nội dung trích xuất từ tài liệu:
Role of pelitinib in the regulation of migration and invasion of hepatocellular carcinoma cells via inhibition of Twist1
Nội dung trích xuất từ tài liệu:
Role of pelitinib in the regulation of migration and invasion of hepatocellular carcinoma cells via inhibition of Twist1
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BMC Cancer Epithelial-mesenchymal transition Hepatocellular carcinoma Cancer metastasis Immunoblotting analysisTài liệu liên quan:
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