The acidic tumor microenvironment enhances PD-L1 expression via activation of STAT3 in MDA-MB-231 breast cancer cells
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Tumor acidosis, a common phenomenon in solid cancers such as breast cancer, is caused by the abnormal metabo‑ lism of cancer cells. The low pH affects cells surrounding the cancer, and tumor acidosis has been shown to inhibit the activity of immune cells.
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BMC Cancer Extracellular acidosis Immune checkpoint Gene set enrichment analysis Immune surveillance mechanismsTài liệu liên quan:
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