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The concentration-independence cellular effects of fibronectin adsorbed on material surfaces with different hydrophobicities

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In tissue engineering, coating biomaterial’s surface with extracellular matrix (ECM) proteins can promote many biological activities, including cellular responses, wound healing, and rejection reduction. Several interactions occur upon binding proteins onto the surfaces, leading to changes in the protein structural conformation, directly affecting the cell-host interactions. Therefore, this study investigates the impacts of surfaces’ wettability on protein conformation.
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The concentration-independence cellular effects of fibronectin adsorbed on material surfaces with different hydrophobicities

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