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Venetoclax combined with low dose cytarabine compared to standard of care intensive chemotherapy for the treatment of favourable risk adult acute myeloid leukaemia (VICTOR): Study protocol for an international, open-label, multicentre, molecularly-guided randomised, phase II trial
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Thông tin tài liệu:
For patients with acute myeloid leukaemia (AML), the only potentially curative treatment is intensive chemotherapy (IC). This is highly toxic, particularly for patients>60 years, potentially leading to prolonged hospitalisations requiring intensive supportive care, and sometimes treatment-related death. This also results in extensive healthcare costs and negatively impacts quality of life (QoL).
Tìm kiếm theo từ khóa liên quan:
BMC Cancer Clinical trial Acute myeloid leukaemia Bayesian non-inferiority design Adaptive design Low-dose cytarabineTài liệu liên quan:
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