Báo cáo khoa học: Aegyptin displays high-affinity for the von Willebrand factor binding site (RGQOGVMGF) in collagen and inhibits carotid thrombus formation in vivo
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Aegyptin is a 30 kDa mosquito salivary gland protein that binds to collagenand inhibits platelet aggregation. We have studied the biophysical propertiesof aegyptin and its mechanism of action. Light-scattering plot showed thataegyptin has an elongated monomeric form, which explains the apparentmolecular mass of 110 kDa estimated by gel-filtration chromatography.
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Báo cáo khoa học: Aegyptin displays high-affinity for the von Willebrand factor binding site (RGQOGVMGF) in collagen and inhibits carotid thrombus formation in vivo
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: Aegyptin displays high-affinity for the von Willebrand factor binding site (RGQOGVMGF) in collagen and inhibits carotid thrombus formation in vivo
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