Báo cáo khoa học: Curcumin suppresses the dynamic instability of microtubules, activates the mitotic checkpoint and induces apoptosis in MCF-7 cells
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In this study, curcumin, a potential anticancer agent, was found to dampenthe dynamic instability of individual microtubules in living MCF-7 cells. Itstrongly reduced the rate and extent of shortening states, and modestlyreduced the rate and extent of growing states. In addition, curcumindecreased the fraction of time microtubules spent in the growing state andstrongly increased the time microtubules spent in the pause state.
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: Curcumin suppresses the dynamic instability of microtubules, activates the mitotic checkpoint and induces apoptosis in MCF-7 cells
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: Curcumin suppresses the dynamic instability of microtubules, activates the mitotic checkpoint and induces apoptosis in MCF-7 cells
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