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The signal transducers and activators of transcription (STATs) convey sig-nals from the membrane to the nucleus in response to cytokines or growthfactors. STAT3 is activated in response to cytokines involved mostly in cellproliferation; STAT1 is activated by cytokines, including interferon-c,involved in defence against pathogens and the inhibition of cell prolifera-tion.
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: Efficient killing of SW480 colon carcinoma cells by a signal transducer and activator of transcription (STAT) 3 hairpin decoy oligodeoxynucleotide – interference with interferon-c-STAT1-mediated killing
