Báo cáo khoa học: Functional role of the linker region in purified human P-glycoprotein
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Human P-glycoprotein (P-gp), which conveys multidrug resistance, is anATP-dependent drug efflux pump that transports a wide variety of struc-turally unrelated compounds out of cells. P-gp possesses a ‘linker region’of75 amino acids that connects two homologous halves, each of whichcontain a transmembrane domain followed by a nucleotide-bindingdomain.
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Báo cáo khoa học: Functional role of the linker region in purified human P-glycoprotein
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Báo cáo khoa học: Functional role of the linker region in purified human P-glycoprotein
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Scientific reports scientific research biochemistry Human P-glycoprotein (P-gp) which conveys multidrug resistance is an ATP-dependent drug efflux pump that transports a wide variety of struc-turally unrelated compounds out of cells. P-gp possesses a ‘linker region’ of75 amino acids that connects two homologous halves each of which contain a transmembrane domain followed by a nucleotide-binding domain.Tài liệu liên quan:
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