Báo cáo khoa học: Functional significance of five noncanonical Ca2+-binding sites of human transglutaminase 2 characterized by site-directed mutagenesis
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The multifunctional tissue transglutaminase 2 (TG2) has a four-domainstructure with several Ca2+-regulated biochemical activities, includingtransglutamylation and GTP hydrolysis. The structure of the Ca2+-bindingform of the human enzyme is not known, and its Ca2+-binding sites havenot been fully characterized.
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: Functional significance of five noncanonical Ca2+-binding sites of human transglutaminase 2 characterized by site-directed mutagenesis
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: Functional significance of five noncanonical Ca2+-binding sites of human transglutaminase 2 characterized by site-directed mutagenesis
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