Phân tích tư tưởng của nhân dân qua đoạn thơ: Những người vợ nhớ chồng… Những cuộc đời đã hóa sông núi ta trong Đất nước của Nguyễn Khoa Điềm
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GTP cyclohydrolase I (GCH) is the rate-limiting enzymefor the synthesis of tetrahydrobiopterin and its activity isimportant in the regulation of monoamine neurotransmit-ters such as dopamine, norepinephrine and serotonin. Wehave studied the action of divalent cations on the enzymeactivity of purified recombinant human GCH expressed inEscherichia coli. First, we showed that the enzyme activity isdependent on the concentration ofMg-freeGTP. Inhibitionof the enzyme activity by Mg2+,aswellasbyMn2+,Co2+or Zn2+, was due to the reduction of the availability ofmetal-free GTP substrate for the enzyme, when a divalentcation was present at a relatively high concentration withrespect toGTP....
Nội dung trích xuất từ tài liệu:
Báo cáo khóa học: GTP cyclohydrolase I utilizes metal-free GTP as its substrate
