Báo cáo khoa học: High levels of structural disorder in scaffold proteins as exemplified by a novel neuronal protein, CASK-interactive protein1
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CASK-interactive protein1 is a newly recognized post-synaptic densityprotein in mammalian neurons. Although its N-terminal region containsseveral well-known functional domains, its entire C-terminal proline-richregion of 800 amino acids lacks detectable sequence homology to anypreviously characterized protein. We used multiple techniques for the struc-tural characterization of this region and its three fragments.
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Báo cáo khoa học: High levels of structural disorder in scaffold proteins as exemplified by a novel neuronal protein, CASK-interactive protein1
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: High levels of structural disorder in scaffold proteins as exemplified by a novel neuronal protein, CASK-interactive protein1
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