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Báo cáo khoa học: Identification and characterization of B¢¢-subunits of protein phosphatase 2 A in Xenopus laevis oocytes and adult tissues Evidence for an independent N-terminal splice variant of PR130 and an extended human PR48 protein

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Protein phosphatase 2A is a phosphoserine/threoninephosphatase implicated inmany cellular processes. The coreenzyme comprises a catalytic and a PR65/A-subunit. Thesubstrate specificity and subcellular localization are deter-mined by a third regulatory B-subunit (PR55/B, PR61/B¢and PR72/130/B¢¢). To identify the proteins of the B¢¢familyinXenopus laevisoocytes, aprophaseXenopusoocyte cDNAlibrarywas screened using humanPR130 cDNAas a probe.Three different classes of cDNAs were isolated....
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Báo cáo khoa học: Identification and characterization of B¢¢-subunits of protein phosphatase 2 A in Xenopus laevis oocytes and adult tissues Evidence for an independent N-terminal splice variant of PR130 and an extended human PR48 protein

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