Báo cáo khoa học: Identification of different isoforms of eEF1A in the nuclear fraction of human T-lymphoblastic cancer cell line specifically binding to aptameric cytotoxic GT oligomers
Số trang: 12
Loại file: pdf
Dung lượng: 368.20 KB
Lượt xem: 2
Lượt tải: 0
Xem trước 2 trang đầu tiên của tài liệu này:
Thông tin tài liệu:
GToligomers, showingadose-dependent cytotoxic effect ona variety of human cancer cell lines, but not on normalhuman lymphocytes, recognize and form complexes withnuclear proteins.By working with human T-lymphoblasticCCRF-CEM cells and by using MS and SouthWesternblotting, we identified eukaryotic elongation factor 1 alpha(eEF1A) as the main nuclear protein that specificallyrecognizes these oligonucleotides.Western blotting andsupershift assays confirmed the nature of this protein andits involvement in forming a cytotoxicity-related complex(CRC)....
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: Identification of different isoforms of eEF1A in the nuclear fraction of human T-lymphoblastic cancer cell line specifically binding to aptameric cytotoxic GT oligomers
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: Identification of different isoforms of eEF1A in the nuclear fraction of human T-lymphoblastic cancer cell line specifically binding to aptameric cytotoxic GT oligomers
Tìm kiếm theo từ khóa liên quan:
scientific reports Report medicine traditional medicine breast cancer medicine chemical reactionTài liệu liên quan:
-
Báo cáo khóa học: The structure–function relationship in the clostripain family of peptidases
10 trang 66 0 0 -
8 trang 52 0 0
-
7 trang 48 0 0
-
14 trang 46 0 0
-
Báo cáo Y học: Mycobacterium tuberculosis FprA, a novel bacterial NADPH-ferredoxin reductase
9 trang 43 0 0 -
11 trang 40 0 0
-
12 trang 40 0 0
-
Báo cáo khoa học: Viral entry mechanisms: cellular and viral mediators of herpes simplex virus entry
9 trang 40 0 0 -
Báo cáo khoa học: Cellular response to unfolded proteins in the endoplasmic reticulum of plants
20 trang 36 0 0 -
12 trang 36 0 0