Phân tích tư tưởng của nhân dân qua đoạn thơ: Những người vợ nhớ chồng… Những cuộc đời đã hóa sông núi ta trong Đất nước của Nguyễn Khoa Điềm
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Intracellularly expressed antibodies (intrabodies) have been used to inhibitthe function of various kinds of protein inside cells. However, problemswith stability and functional expression of intrabodies in the cytosol remainunsolved. In this study, we show that single-chain variable fragment (scFv)intrabodies constructed with a heavy chain variable (VH) leader signalsequence at the N-terminus were translocated from the endoplasmic reti-culum into the cytosol of T lymphocytes and inhibited the function ofthe target molecule, Wiskott–Aldrich syndrome protein (WASP)....
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: Intrabodies against the EVH1 domain of Wiskott–Aldrich syndrome protein inhibit T cell receptor signaling in transgenic mice T cells
