Danh mục

Báo cáo khoa học: Modulation of cyclin D1 and early growth response factor-1 gene expression in interleukin-1b-treated rat smooth muscle cells by n-6 and n-3 polyunsaturated fatty acids

Số trang: 12      Loại file: pdf      Dung lượng: 431.12 KB      Lượt xem: 6      Lượt tải: 0    
Xem trước 2 trang đầu tiên của tài liệu này:

Thông tin tài liệu:

The proliferation of smooth muscle cells (SMC) is a keyevent in the development of atherosclerosis. In addition togrowth factors or cytokines, we have shown previously thatn-3 polyunsaturated fatty acids (PUFAs) act in oppositionto n-6 PUFAs by modulating various steps of the inflam-matory process. We have investigated the molecular mech-anisms by which the incorporation of the n-6 PUFA,arachidonic acid, increases the proliferation of rat SMCtreated with interleukin-1b, while the n-3 PUFAs eicosa-pentaenoic acid (EPA) and docosahexaenoic acid (DHA),elicit nomitogenic response. ...
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: Modulation of cyclin D1 and early growth response factor-1 gene expression in interleukin-1b-treated rat smooth muscle cells by n-6 and n-3 polyunsaturated fatty acids

Tài liệu được xem nhiều: