Báo cáo khoa học: Oxidative neuronal injury The dark side of ERK1/2
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The extracellular signal regulated protein kinases (ERK1/2)are essential for normal development and functional plasti-city of the central nervous system. However, a growingnumber of recent studies in models of cerebral ischemia,brain trauma and neurodegenerative diseases implicate adetrimental role for ERK1/2 signaling during oxidativeneuronal injury. Neurons undergoing oxidative stress-rela-ted injuries typically display a biphasic or sustained patternof ERK1/2 activation. A variety of potential targets ofreactive oxygen species and reactive nitrogen species couldcontribute to ERK1/2 activation....
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Báo cáo khoa học: Oxidative neuronal injury The dark side of ERK1/2
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Báo cáo khoa học: Oxidative neuronal injury The dark side of ERK1/2
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