Báo cáo khoa học: Phosphorylation of hormone-sensitive lipase by protein kinase A in vitro promotes an increase in its hydrophobic surface area
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Hormone-sensitive lipase (EC 3.1.1.79; HSL) is a key enzyme in the mobili-zation of fatty acids from stored triacylglycerols. HSL activity is controlledby phosphorylation of at least four serines. In rat HSL, Ser563, Ser659 andSer660 are phosphorylated by protein kinase A (PKA)in vitro as well asinvivo, and Ser660 and Ser659 have been shown to be the activity-controllingsites in vitro.
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Báo cáo khoa học: Phosphorylation of hormone-sensitive lipase by protein kinase A in vitro promotes an increase in its hydrophobic surface area
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Báo cáo khoa học: Phosphorylation of hormone-sensitive lipase by protein kinase A in vitro promotes an increase in its hydrophobic surface area
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