Báo cáo khoa học: Pigment epithelium-derived factor binds to cell-surface F1-ATP synthase
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Pigment epithelium-derived factor (PEDF), a potent blocker of angiogene-sis in vivo, and of endothelial cell migration and tubule formation, bindswith high affinity to an as yet unknown protein on the surfaces of endothe-lial cells. Given that protein fingerprinting suggested a match of a60 kDa PEDF-binding protein in bovine retina withBos taurusF1-ATPsynthase b-subunit, and that F1Fo-ATP synthase components have beenidentified recently as cell-surface receptors, we examined the direct bindingof PEDF to F1. ...
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Báo cáo khoa học: Pigment epithelium-derived factor binds to cell-surface F1-ATP synthase
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Báo cáo khoa học: Pigment epithelium-derived factor binds to cell-surface F1-ATP synthase
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