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Báo cáo khoa học: Redox reaction between amino-(3,4-dihydroxyphenyl)methyl phosphonic acid and dopaquinone is responsible for the apparent inhibitory effect on tyrosinase
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Amino-(3,4-dihydroxyphenyl)methyl phosphonic acid, thephosphonic analogof 3,4-dihydroxyphenylglycine, hadbeenpreviously reported as a potent inhibitor of tyrosinase. Themechanism of the apparent enzyme inhibition by this com-pound has now been established. Amino-(3,4-dihydroxy-phenyl)methyl phosphonic acid turned out to be a substrateand was oxidized too-quinone, which evolved to a finalproduct identified as 3,4-dihydroxybenzaldehyde, the sameas for 3,4-dihydroxyphenylglycine.
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: Redox reaction between amino-(3,4-dihydroxyphenyl)methyl phosphonic acid and dopaquinone is responsible for the apparent inhibitory effect on tyrosinase
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: Redox reaction between amino-(3,4-dihydroxyphenyl)methyl phosphonic acid and dopaquinone is responsible for the apparent inhibitory effect on tyrosinase
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