Báo cáo khoa học: The enzymatic activity of SR protein kinases 1 and 1a is negatively affected by interaction with scaffold attachment factors B1 and 2
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SR protein kinases (SRPKs) phosphorylate Ser⁄Arg dipeptide-containingproteins that play crucial roles in a broad spectrum of basic cellular processes.Phosphorylation by SRPKs constitutes a major way of regulating such cellu-lar mechanisms. In the past, we have shown that SRPK1a interacts with thenuclear matrix protein scaffold attachment factor B1 (SAFB1) via its uniqueN-terminal domain, which differentiates it from SRPK1.
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Báo cáo khoa học: The enzymatic activity of SR protein kinases 1 and 1a is negatively affected by interaction with scaffold attachment factors B1 and 2
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: The enzymatic activity of SR protein kinases 1 and 1a is negatively affected by interaction with scaffold attachment factors B1 and 2
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