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Glutamine is an essential amino acid for enterocytes, especially in states ofcritical illness and injury. In several studies it has been speculated that thebeneficial effects of glutamine are dependent on the route of supply (lumi-nal or systemic). The aim of this study was to investigate the relevance ofboth routes of glutamine delivery toin vitro intestinal cells and to explorethe molecular basis for proposed beneficial glutamine effects: (a) by deter-mining the relative uptake of radiolabelled glutamine in Caco-2 cells;...
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Báo cáo khoa học: Differentiation stage-dependent preferred uptake of basolateral (systemic) glutamine into Caco-2 cells results in its accumulation in proteins with a role in cell–cell interaction
